Andrew H Resnick, Ph. D
A_RESNICK.jpg
 Title: Assistant Professor
 Dept: Physics
 Office: SI 121
 Phone: 216-687-2437,  216-687-2437
 Email: A.RESNICK@csuohio.edu
 Web: http://resnicklab.wordpress.com/
 Address: 2121 Euclid Ave. SI 121, Cleveland, OH 44115

Courses Taught

Publications


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Research Keywords:
Mechanosensation, Optical trapping, Microscopy, Polarimetry, Cystic Fibrosis, Polycystic Kidney Disease, Primary Cilium, Fourier Optics
 
Education:
B.S., Physics, Rensselaer Polytechnic Institute, 1991
Ph.D., Physics, University of Alabama in Huntsville, 1997
Instructor, Physiology, Case Western Reserve University, 2009
 
Brief Bio:
My research activity has two main tracks: the role of sensory cilia in cellular mechanosensation and optical probes of matter.  Experimental tools we use include epithelial cell culture and electrophysiology, microscopy and laser tweezers, microfluidics and analytical modeling. Biological systems under investigation include renal and airway epithelial tissue.  We have many small-scale startup and feasibility experiments as well, so if you are a motivated student with an interest in learning many essential laboratory techniques, please stop by!
 
Honors and Awards:
2014         Faculty Merit Recognition Award
2011-present   NIH R15 Research Award
2003-2008 NIH K25 Mentored Quantitative Research Award
2005 Research ShowCASE outstanding Postdoctoral Poster award
2000         Member, Outstanding Technical Team for Mine Detection Data Collection
1993-1997 NASA Graduate Student Research Program Grant
 
Teaching Areas:
2009-Present Assistant Professor, Department of Physics, Cleveland State University
        PH221, PH222, PH455/555

2003-2009 Instructor, Department of Physiology and Biophysics, CWRU
                Anat/Phol 517, Optical Imaging and Microscopy for Biologists, 2003
                Anat/Phol 517, Optical Imaging and Microscopy for Biologists, 2004
                PHOL 476, Cellular Biophysics, Spring 2005
                PHOL 476, Cellular Biophysics, Spring 2006
                PHOL 476, Cellular Biophysics, Spring 2007
                MBIO 525, Advances in Biological Imaging, Fall 2006
                GENE 537, Light and Video Microscopy, Fall 2007
                Block 2 small group, Cell signaling, 8/25/08
                Block 2 small group, Cell signaling, 8/27/07

2000-2001 Lecturer, Department of Physics, Case Western Reserve University.
              
                PHYS 115, Physics I, Summer 2000
                PHYS 115, Physics I, and PHYS 121, Mechanics, Fall 2000

1997-1999 Research Scientist, Nichols Research Corporation

                Infrared phenomenology (in-house training)
                Polarization and Polarimetry (in-house training)
 
Professional Affiliations:
Optical Society of America (1997-current)
American Physical Society (1992-current)
American Physiological Society (2003- current)
Sigma Xi (2006-current)
 
Professional Experience:
2005-2009 Instructor, Department of Physiology and Biophysics, Case Western Reserve University
2004-2005 Post-doctoral Fellow, Department of Physiology and Biophysics (CWRU)

The role of sensory cilia in cellular mechanosensation. Systems under investigation include renal and airway epithelial tissue. Primary experimental probes are laser tweezers, microscopy, and two-sided perfusion chambers.

2003-2004 Research Staff, National Center for Microgravity Research at NASA Glenn Research Center
1999- 2003 Senior Scientist, Northrop Grumman at NASA Glenn Research Center

Participant in NASA projects including Ultraviolet-Visible-Infrared Spectrometer (UVIS), Vapor Phase Catalytic Ammonia Removal (VPCAR), Soft condensed matter program group, Bioscience New Directions.
Senior member of the Light Microscopy Module (LMM) development team, responsible for the development of a fully automated microscope.
Development of novel instrumentation (laser tweezers), spaceflight modifications to new microscopy technologies (confocal microscopy, spectrophotometer), and static and dynamic light scattering.
Direct experience with a wide range of equipment including solid-state lasers, fiber optic systems, optical test and measurement equipment, acousto-optic and electro-optic modulators, digital cameras and interfaces, image processing and optical system design.
Participated in several KC-135 reduced gravity flights, experienced over 400 zero-g parabolas.

1997 - 1999 Research Scientist, Nichols Research Corporation

Responsible for the development of an accurate physical model for passive and active sensor simulations. Added polarization effects, millimeter wave imaging, rough surface scattering and improved thermal flow models.
Developed and used a dual rotating retarder Mueller matrix spectropolarimeter with the goal of obtaining highly accurate and precise surface scattering measurements.

1992- 1997 Experimental investigation into dynamic behavior of contact line and contact angle of liquid bridges (Ph.D. dissertation).

Fundamental research of a basic physical phenomena (liquid bridges) common to many technological processes, e.g. floating-zone crystal growth, fluid flow in porous materials, and adhesion
Constructed a neutral buoyancy (Plateau) tank, computer controlled motion equipment, Schlieren, Fourier, and imaging optical systems
Developed innovative and accurate measurements of contact angle and interfacial energy in reduced gravity conditions
 
Research Grants:
Grant Number: Cleveland State University Faculty Innovation Fund  Program
Project Title:  Microperfusion Tissue Interrogator: platform technology development (PI)

Proposal Number: NSF 1337859
Proposal Title: MRI: Acquisition of an integrated atomic force microscope/ Inverted optical microscope for interdisciplinary research at Cleveland State University
Principal Investigator: Chandrasekhar Kothapalli
Co-PI(s): Andrew Resnick (Co-Principal Investigator)
Xue-Long Sun (Co-Principal Investigator)
Orhan Talu (Co-Principal Investigator)
Nolan Holland (Co-Principal Investigator)

Proposal Number: NSF 1161152
Proposal Title: Mathematics Achievement as a STEP for STEM Success
Principal Investigator: John Holcomb
Co-PI(s): Andrew Resnick, Debbie Jackson, Stephen Duffy

Grant Number: NIH 1 R15 DK092716-01
Project Title:  Fluid flow is an environmental modifier of ADPKD
Project dates: May 1, 2011- April 30, 2014

Grant Number: Cleveland State University GRHD Faculty Development Program
Project Title:  Microfluidic Fabrication Facility
Project dates: June 1, 2013- July 31, 2014

Grant Number: Cleveland State University Faculty Development Program
Project Title:  The Primary Cilium Mediates Cellular Mechanosensation
Project dates: July 1, 2011- June 30, 2012
Award amount: $19,797

CSU Summer student Provost fund awards, 2010 and 2011

Grant Number: 1 K25 DK071027-01 (NIH/NIDDK)
Project Title:  Flow Effects on Primary Cilium Deflection
Project dates: July 1, 2005- June 30, 2010

Grant Number: Cystic Fibrosis Foundation R447-CR02
Project Title: Role of Primary Cilium in Airway Surface Liquid Regulation
Project dates: July 1, 2006-June 30, 2008

NIH NCRR Shared Instrumentation Grant Program
Project Title: Upright Light Microscope Workstation
Project dates: 4/1/2006-3/31/2007