Aaron Frederick Severson (Aaron), Ph. D
 Title: Assistant Professor
Adjunct Staff, Department of Molecular Genetics, Cleveland Clinic
 Dept: Biological, Geological and Environmental Sciences
 Office: SR 275,276
 Phone: 216-687-4864
 Email: A.SEVERSON@csuohio.edu
 Web: http://www.csuohio.edu/grhd/faculty/aaron-severson
 Address: 2121 Euclid Ave. SR 275,276, Cleveland, OH 44115

Courses Taught


Faculty Only:
Update Profile

Ph.D., Biology, University of Oregon, 2001
B.S., Biology, University of Wisconsin, 1994
Brief Bio:
In all organisms, accurate transmission of the genome during cell division is essential to prevent genetic instability. This is especially true during meiosis, the process that reduces genome copy number, or ploidy, from two in diploid germline stem cells to one in each haploid gamete. Defects in meiosis affect all cells of an embryo and profoundly impact health: it is estimated that over 30% of human zygotes have abnormal chromosomal content at conception, and such aneuploidies are the leading known cause of miscarriages and birth defects. The best known viable aneuploidy, trisomy 21, causes Down syndrome. I use Caenorhabditis elegans to study how gametes inherit exactly one copy of every chromosome. Because the process of meiosis is widely conserved among eukaryotes, the meiotic mechanisms we identify in the lowly worm are relevant to understanding gametogenesis in humans.
Honors and Awards:
Helen Hay Whitney Foundation Postdoctoral Fellowship, 2003-2006
American Society for Cell Biology Predoctoral Student Travel Award, 1999
John O. Ward Scholarship, 1990-1994
Dean's List, University of Wisconsin, 1990 and 1992
Professional Affiliations:
American Society for Cell Biology
Genetics Society of America
Professional Experience:
2013-Present Adjunct Staff, Department of Molecular Genetics, Cleveland Clinic
2013-Present Member, Cleveland State University Graduate Faculty
2013-Present Member, Center for Gene Regulation in Health and Disease (GRHD)
2012-Present Assistant Professor, Cleveland State University, BGES Department
2006-2012 Associate Specialist, University of California, MCB Department
2002-2006 Postdoctoral Researcher, University of California, MCB Department