Brian L Woodside, Ph.D.
 Title: College Associate Lecturer
 Dept: Psychology
 Office: UN 258
 Phone: 216-687-3503,  (216)687-3503
 Address: 2121 Euclid Ave. UN 258, Cleveland, OH 44115

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Research Keywords:
Synaptic Plasticity, Learning and Memory, Long-term Potentiation, Neuro-electrophysiology
B.A., Psychology, University of Akron, 1995
Ph.D., Biomedical Sciences/ Behavioral Neuroscience, Kent State University in collaboration with Northeastern Ohio Universities College of Medicine, 2002
Brief Bio:
Brian Woodside earned his Ph.D. in Biomedical Sciences/Behavioral Neuroscience from Kent State University in collaboration with Northeastern Ohio Universities College of Medicine, and completed postdoctoral research at Bowling Green State University.  Brian has had extensive teaching and laboratory experience, has supervised both undergraduate and graduate research, and has successfully written grants to support his research.
Research Interests:
I am interested in the physiological mechanisms of synaptic plasticity and their behavioral correlates. Specifically, I am interested in the effects of normal aging, brain injury, dementia, and drug abuse on cognitive processes, principally learning and memory formation.

Considerable experimental evidence supports the hippocampal system¿s role in behavioral tasks involving acquisition of certain types of information and its flexible representations. An enduring enhanced neuronal response called long-term potentiation (LTP), which can be induced behaviorally, or experimentally by a tetanus stimulus, is considered one possible mechanism of learning and encoding long-term memories. At least two forms of LTP with different induction kinetics and different signal transduction cascades have been identified in the hippocampus of rats. These two distinct forms of LTP in the hippocampus, one mediated by NMDA receptors (NMDAR) and the other by voltage-dependent calcium channels (VDCC), may be instrumental at different stages of learning and memory consolidation.

My current research follows several different paths. I plan to incorporate single-cell recording of place fields into my LTP research by combining pharmacological antagonists with cellular recording techniques to examine the different roles of NMDARs and VDCCs in the hippocampus while plastic changes occur in free moving animals.
In a collaborative research project with Dr. Jon Sprague we have established an animal model for the learning and memory deficits that occur from serotonergic neurotoxicity after chronic MDMA (ecstasy) use. Currently we plan to examine how this damage may affect hippocampal LTP.

Additional research will use EEG recording to study LTP in the human somatosensory and motor cortices.
Teaching Areas:
Introduction to the Science of Psychology, Cognition and the Brain, Memory and Cognition, Sensation and Perception, Psychopharmacology, Behavioral Neuroscience
Professional Affiliations:
Society for Neuroscience
Faculty for Undergraduate Neuroscience
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