| Title: |
Professor
Professor of Molecular Genetics, Center for Gene Regulation in Health and Disease |
| Dept: | Biological, Geological and Environmental Sciences |
| Office: | SI 263 |
| Phone: | 216-687-2435 |
| Fax: | 216-687-6972 |
| Email: | B.MAZUMDER@csuohio.edu |
| Address: | 2121 Euclid Ave. SI 263, Cleveland, OH 44115 |
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| Education: | ||||||||
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B.S., Chemistry Major, Burdwan University, India, 1979
M.S., Organic Chemistry, Visva Vharati University, India, 1982 M. Phil, Applied Chemistry, Indian School of Mines, India, 1984 Ph.D., Biochemistry, Bose Institute, India, 1989 | ||||||||
| Brief Bio: | ||
| POST-GRADUATE TRAINING AND PROFESSIONAL EXPERIENCE
1989-1991 Senior Technical Assistant, Geochemistry Division, Geological Survey of India, India. 1991-1992 Postdoctoral Fellow, Department of Pharmacology, University of Minnesota. 1992-1994 Postdoctoral Fellow, Department of Molecular Biology, Cleveland Clinic Foundation Research Institute, Cleveland, OH 1994-2001 Research Associate, Department of Cell Biology, Cleveland Clinic Foundation Lerner Research Institute, Cleveland, OH. 2001-Aug. 2004 Project Scientist, Department of Cell Biology, Cleveland Clinic Foundation Lerner Research Institute. August 2004 - May 2008 Assistant Professor, Department of Biology, Cleveland State University, Cleveland, OH August 2004 - Adjunct Faculty (Present Position), Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Cleveland, OH. May 2008 -August 2013 Associate Professor Center for Gene Regulation in Health and Disease, Department of Biology, Cleveland State University, Cleveland, OH August 2013 - Professor (Present Position), Center for Gene Regulation in Health and Disease, Department of Biology, Cleveland State University, Cleveland, OH | ||
| Honors and Awards: | ||
| HONORS AND AWARDS
2000 Elsa Albrecht Fellow Award (given each year from the department of cell biology at CCFLRI for outstanding publication) 2000 F. Merlin Bumpus Junior Investigator award in Basic Science for outstanding research and excellence in presentation. 2001 Scientist Development Grant Award from American Heart Association. 2005-2010 RO1 grant award from National Institute of Health 2005-2009: Served as a Research Study Section Member of American Heart Association for the review of grants 2006 Recipient of Faculty Merit Award of Cleveland State University. 2006 Recipient of Outstanding Research Award of College of Science, Cleveland State University. 2007 Recipient of Faculty Merit Award . 2008 Recipient of Grant-in-Aid Award from American Heart Association. 2009 Recipient of Faculty Merit Award . 2010 Served as an Ad hoc Reviewer of National Science Foundation. 2010 Recipient of Distinguished Faculty Award for Research. 2010-2015 RO1 grant Award from National Institute of Health, National Heart Lung and Blood Institute 2010 Distinguished Faculty Award for Research, Cleveland State University 2012-2014 : Recipient of Faculty Merit Award 2015-2020 RO1 grant Award from National Institute of Health, National Heart Lung and Blood Institute | ||
| Research Interests: | ||
| CURRENT RESEARCH INTERESTS
Mechanisms of anti-viral innate immunity Post-transcriptional regulation as a mechanism for resolution of inflammation. Molecular mechanisms of the pathogenesis of Cardiovascular Disease and Gastrointestinal Disease Basic mechanisms of Translation Control and Ribosome Biogenesis. | ||
| Teaching Areas: | ||
| TEACHING INTERESTS
Advanced: Post-transcriptional regulation of gene expression. Molecular mechanisms of atherosclerosis. General: Molecular Biology, Biochemistry, Cell Biology and Virology. | ||
| Professional Affiliations: | ||
| Adjunct Faculty of the Department of Cellular and Molecular Medicine. Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio
Adjunct Faculty of the Center for RNA Research, Case Western Reserve University School of Medicine | ||
| Professional Experience: | ||
| Teaching in Graduate courses
Development of new courses from the recently published scientific papers Supervision of graduate students and postdoctoral fellows Securing funds for research from external funding agencies. | ||
| University Service: | ||
| Member, Research Challenge Committee
Member, Faculty Senate Member, University Peer Review Committee (UPRC) Member, Institutional Animal Use and Care Committee (IACUC) | ||
| Professional Service: | ||
| PROFESSIONAL SERVICE TO THE SCIENTIFIC COMMUNITY
(a) Served as a member of study section of American Heart Association Research Study Committee 2005 - 2009. (b) Served as an ad-hoc reviewer of Journal of Biological Chemistry, Journal of Immunology, Cellular Microbiology, Molecular and Cellular Biology, RNA, Journal of Lipid Research, Molecular and Cellular Biochemistry, BMC Microbiology, Stem Cells & Development, PLOS (c) Reviewer of National Science Foundation (d) Reviewer of Israel Science Foundation (e) Reviewer of Quatar Foundation (f) Reviewer of James and Esther King Florida Biomedical Research Program, Technology Transfer / Commercialization Partnership Grants (g) Reviewer of CZECH Science Foundation (h) Served as a member of the National American Heart Association Basic Immunology Review Committee | ||
| Research Grants: | ||
| Extramural Funding:
Active: NIH, NIAID R21 Title: ¿Translational regulation of SARS-CoV-2 in response to viral S protein-induced signaling. Total Amount: $408,375 Grant ID: R21AI173187 Role: Principal Investigator, Type of Grant: R21 Duration: 08-14-2023 to 07-31-2025 Past: 1. Principal Investigator of American Heart Association Scientist Development Grant ($260,000 for 4 years); 01-01-2001 to 31-12-2004. 2. RO1 Grant Funded by National Heart Lung and Blood Institute (National Institute of Health): Translational Silencing in Monocytes: Role of L13a (1 Million dollar direct cost for 5 years); 03-01-2005 to 08-22-2010. Role: Principal Investigator 3. Grant-in-Aid Funded by American Heart Association: Resolution of Cellular Inflammation: Role of Translational Silencing ($121,000 direct cost for 2 years); 07-01-2008 to 06-30-2010. Role: Principal Investigator 4. Ohio Research Council / Ohio Board of Regents Title: Role of Inflammation in Atherosclerosis, Grant ID# 0230-0223-10 WEYMA15G Period: 03/20/2011 ¿ 03/19/2012, Total Direct Cost: $38,000 5. National Heart Lung and Blood Institute, National Institute of Health RO1 Grant; Translational Silencing in Monocytes: Role of L13a; (1.8 Million dollar) 08-23-2010 to 04-30-2016 . Role: Principal Investigator 6. National Heart Lung and Blood Institute, National Institute of Health RO1 Grant; Translational Silencing in Monocytes: Role of L13a (1.45 Million dollar) 05-01-2016 to 02-28-2022 . (Competing Renewal) Role: Principal Investigator Extramural Funding Awarded to Support the Trainees in my Laboratory: 1. American Heart Association Postdoctoral Fellowship: Awarded to support Dr. Sujan Chaudhury. Title: Translational silencing in Monocytes and Genome wide screening of its target mRNAs. $86,000 for 2 years; 07-01-2007 to 06-30-2009. Role: Sponsor and Principal Research Supervisor. 2. American Heart Association Predoctoral Fellowship: Awarded to support Priyanka Das. Title: Extra-ribosomal function of ribosomal protein L13a in translational silencing and monocyte mediated oxidation of LDL. $42,000 for two years; 07-01-2008 to 06-30-2010. Role: Sponsor and Principal Research Supervisor. 3. American Heart Association Predoctoral Fellowship: Awarded to support Darshana Poddar. Title: Macrophage-specific KO moue of L13a: Evaluation of its potential to be a novel model for uncontrolled inflammation. $46,000 for 2 years; 07-01-2011 to 06-30-2013. Role: Sponsor and Principal Research Supervisor | ||