Barsanjit Mazumder, Ph.D
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 Title: Professor
Professor of Molecular Genetics, Center for Gene Regulation in Health and Disease
 Dept: Biology, Geology, Environmental Science
 Office: SI 261,269
 Phone: 216-687-2435
 Fax: 216-687-6972
 Email: B.MAZUMDER@csuohio.edu
 Address: 2121 Euclid Ave. SI 261,269, Cleveland, OH 44115

Courses Taught

Publications


Faculty Only:
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Research Keywords:
Post-transcriptional regulation, Inflammation, Atherosclerosis, Macrophage, Monocyte, Translational regulation, Ribosome, Ribosomal protein, rRNA modifications
 
Education:
B.S., Chemistry Major, Burdwan University, India, 1979
M.S., Organic Chemistry, Visva Vharati University, India, 1982
M. Phil, Applied Chemistry, Indian School of Mines, India, 1984
Ph.D., Biochemistry, Bose Institute, India, 1989
 
Brief Bio:
POST-GRADUATE TRAINING AND PROFESSIONAL EXPERIENCE
1989-1991 Senior Technical Assistant, Geochemistry Division, Geological Survey of India, India.
1991-1992 Postdoctoral Fellow, Department of Pharmacology, University of Minnesota.
1992-1994 Postdoctoral Fellow, Department of Molecular Biology, Cleveland Clinic Foundation      Research Institute, Cleveland, OH
1994-2001 Research Associate, Department of Cell Biology, Cleveland Clinic Foundation Lerner Research Institute, Cleveland, OH.
2001-Aug. 2004 Project Scientist, Department of Cell Biology, Cleveland Clinic Foundation Lerner     Research Institute.
August 2004 - May 2008 Assistant Professor, Department of Biology, Cleveland State University, Cleveland, OH
August 2004 - Adjunct Faculty (Present Position), Department of Molecular Medicine, Cleveland Clinic Lerner  College of Medicine, Cleveland, OH.
May 2008 -August 2013 Associate Professor Center for Gene Regulation in Health and Disease, Department of Biology, Cleveland State University, Cleveland, OH
August 2013 - Professor (Present Position), Center for Gene Regulation in Health and Disease, Department of Biology, Cleveland State University, Cleveland, OH
 
Honors and Awards:
HONORS AND AWARDS
2000 Elsa Albrecht Fellow Award (given each year from the department of cell biology at CCFLRI for outstanding publication)
2000 F. Merlin Bumpus Junior Investigator award in Basic Science for outstanding research and excellence in     presentation.
2001       Scientist Development Grant Award from American Heart Association.
2005       RO1 grant award from National Institute of Health
2005-2009: Served as a Research Study Section Member of American Heart Association for the review of grants
2006 Recipient of Faculty Merit Award of Cleveland State University.
2006 Recipient of Outstanding Research Award of College of Science, Cleveland State University.
2007       Recipient of Faculty Merit Award .
2008       Recipient of Grant-in-Aid Award from American Heart Association.
2009       Recipient of Faculty Merit Award .
2010       Served as an Ad hoc Reviewer of National Science Foundation.
2010       Recipient of Distinguished Faculty Award for Research.
2010       RO1 grant Award from National Institute of Health, National Heart Lung and Blood Institute
2010        Distinguished Faculty Award for Research, Cleveland State University
2012-2014 : Recipient of Faculty Merit Award
 
Research Interests:
CURRENT RESEARCH INTERESTS

Mechanisms of anti-viral innate immunity
Post-transcriptional regulation as a mechanism for resolution of inflammation.
Molecular mechanisms of the pathogenesis of Cardiovascular Disease and Gastrointestinal Disease

Basic mechanisms of Translation Control and Ribosome Biogenesis.
 
Teaching Areas:
TEACHING INTERESTS
Advanced: Post-transcriptional regulation of gene expression.
                  Molecular mechanisms of atherosclerosis.
General:   Molecular Biology, Biochemistry, Cell Biology and Virology.
 
Professional Affiliations:
Adjunct Faculty of the Department of Cellular and Molecular Medicine. Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio

Adjunct Faculty of the Center for RNA Research, Case Western Reserve University School of Medicine
 
Professional Experience:
Teaching in Graduate courses

Development of new courses from the recently published scientific papers

Supervision of graduate students and postdoctoral fellows

Securing funds for research from external funding agencies.
 
University Service:
Member, Research Challenge Committee
Member, Faculty Senate
Member University Peer Review Committee (UPRC)
 
Professional Service:
PROFESSIONAL SERVICE TO THE SCIENTIFIC COMMUNITY

(a) Served as a member of study section of American Heart Association Research Study Committee 2005 - 2009.

(b) Served as an ad-hoc reviewer of Journal of Biological Chemistry, Journal of Immunology, Cellular Microbiology, Molecular and Cellular Biology, RNA, Journal of Lipid Research, Molecular and Cellular Biochemistry, BMC Microbiology, Stem Cells & Development

(c) Reviewer of National Science Foundation

(d) Reviewer of Israel Science Foundation

(e) Reviewer of Quatar Foundation

(f) Reviewer of James and Esther King Florida Biomedical Research Program, Technology Transfer / Commercialization Partnership Grants

(g) Reviewer of CZECH Science Foundation
 
Research Grants:
Extramural Funding:

Past:
1. Principal Investigator of American Heart Association Scientist Development Grant ($260,000 for 4 years); 01-01-2001 to 31-12-2004.

2. RO1 Grant Funded by National Heart Lung and Blood Institute (National Institute of Health): Translational Silencing in Monocytes: Role of L13a (1 Million dollar direct cost for 5 years); 03-01-2005 to 08-22-2010.
Role: Principal Investigator

3. Grant-in-Aid Funded by American Heart Association: Resolution of Cellular Inflammation: Role of Translational Silencing ($121,000 direct cost for 2 years); 07-01-2008 to 06-30-2010.
Role: Principal Investigator

4. Ohio Research Council / Ohio Board of Regents
Title: Role of Inflammation in Atherosclerosis, Grant ID# 0230-0223-10 WEYMA15G
Period: 03/20/2011 ┬┐ 03/19/2012, Total Direct Cost: $38,000


Active:
National Heart Lung and Blood Institute, National Institute of Health RO1 Grant ┬┐Translational Silencing in Monocytes: Role of L13a┬┐ (1.8 Million dollar total cost for 5 years)
08-23-2010 to 04-30-2015 (Scored top 8 percentile in NIH Peer Review).  
Role: Principal Investigator


Extramural Funding Awarded to Support the Trainees in my Laboratory:

1. American Heart Association Postdoctoral Fellowship: Awarded to support Dr. Sujan Chaudhury. Title: Translational silencing in Monocytes and Genome wide screening of its target mRNAs. $86,000 for 2 years; 07-01-2007 to 06-30-2009.
Role: Sponsor and Principal Research Supervisor.

2. American Heart Association Predoctoral Fellowship: Awarded to support Priyanka Das. Title: Extra-ribosomal function of ribosomal protein L13a in translational silencing and monocyte mediated oxidation of LDL. $42,000 for two years; 07-01-2008 to 06-30-2010.
Role: Sponsor and Principal Research Supervisor.

3. American Heart Association Predoctoral Fellowship: Awarded to support Darshana Poddar. Title: Macrophage-specific KO moue of L13a: Evaluation of its potential to be a novel model for uncontrolled inflammation. $46,000 for 2 years; 07-01-2011 to 06-30-2013.
Role: Sponsor and Principal Research Supervisor