| Title: | Assistant Professor |
| Dept: | Chemistry |
| Office: | SR 359 |
| Phone: | 216-687-2473 |
| Email: | j.gonzales22@csuohio.edu |
| Web: | https://www.gonzalesarevalo-lab.com/ |
| Blog: | https://www.csuohio.edu/grhd/faculty/junior-gonzales |
| Address: | 2121 Euclid Ave. SR 359, Cleveland, OH 44115 |
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| Education: | ||||||||
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B.A., Biochemistry, Hunter College of The City University of New York, 2011
Ph.D., Chemistry, The Graduate School of The City University of New York, 2017 Post-Doctoral, Radiology, Memorial Sloan Kettering Cancer Center, 2022 | ||||||||
| Brief Bio: | ||
| (+) Dr. Junior Gonzales is an Assistant Professor at the Department of Chemistry at Cleveland State University, Ohio. His lab automates/revolves around the development of fluorescent and radioactive synthetic probes based on bio-tropical peptides to quantify molecular variations of ion channels linked to nascent neuropathies and/or cancer. He was born in Iquitos, Peru, in the Amazon rainforest, and continued to evolve in Bushwick, Brooklyn. He is a motivated independent researcher employing nuclear imaging to deploy targeting tracers in the study of peripheral nerves, pain afflictions, cancer and infections.
(++) Dr. Gonzales attended Queensborough Community College, majoring in chemistry. In 2008, He became a MARC scholar at Hunter College of the City University of New York (CUNY), where he received his Bachelor's degree in biochemistry. In 2017, he obtained his PhD in chemistry from the Graduate School and University Center of CUNY, where he built his interest in near infrared dyes, chelations and biomedical applications with porphyrin sensors. The same year, he joined the Radiology Department of Memorial Sloan Kettering Cancer Center, where he was trained in the translation of his synthetic probes from the bench to the pre-clinical setting. In 2021, Junior was named to SNMMI's "Ones to Watch 2021", a national award recognizing outstanding young scientists in the nuclear and molecular imaging field. The same year he was awarded the NIH MOSAIC K99/R00 grant to start his independent research. | ||
| Honors and Awards: | ||
| ** National Institute of Health, Research Initiative for Minority Students, RIMS Fellowship, 2006-07
** National Institute of Health, Minority Access to Research Careers, MARC Fellowship, 2008-10 ** CUNY, The Belle Vader Mascots Award for Undergraduate Research, 2010 ** National Institute of Health, Research Initiative for Scientific Career, RISE Fellowship, 2012-14 ** Rutgers University, The Morgan Scholar, 2014 ** National Science Foundation, Integrative Graduate Education Research Traineeship, IGERT, 2014-15 ** National Institute of Health, Clinical & Translational Science Center Fellowship TL1, CTSC, 2015-17 ** National Institute of Health, Diversity Supplement, Postdoctoral Scholar Grant, 2018-20 ** Society of Nuclear Medicine and Molecular Imaging, Ones to Watch, 2020 ** National Institute of Health, NIH-MOSAIC K99R00, Independence Transition Grant, 2021-22 | ||
| Creative and Activities: | ||
| Patents:
1. Gonzales, J., Hernandez-Gil, J., Lewis, J., Reiner, T. 'Imaging Compounds Selective for NaV1.7.' US Patent Appl. 18/009,699, published Aug 03rd, 2023. Patent No 18009699 2. Gonzales, J., Demetrio de Souza Franca, P., Lewis, J., Reiner, T., King, G. 'Proteins and Fluorophore-containing Compounds Selective for NaV1.7.' US Patent Appl. 17/423,341, published Mar 03rd, 2022. Patent No 17423341 3. Gonzales, J., Bhupathiraju, N. V., Drain, C. D. 'Chlorins and Phthalocyanines for Biological Applications.' US Prov. Patent Appl., filed Nov 1, 2016. Patent No 62/251,828 | ||
| Research Interests: | ||
| (++) Revalidating the ideas, of finding contemporaneous physiochemical tools and cures in the Peruvian rainforest, while considering it, the largest in-situ Bio-chemical laboratory, is a core responsibility for our research. We use bio-tropical peptides to accost neuropathies and cancer with a heavy use of organic chemistry, re-engineered peptide synthesis, in-vivo validation and molecular imaging. | ||
| Teaching Areas: | ||
| Organic Chemistry and Advance Organic Chemistry | ||
| Professional Affiliations: | ||
| 1. World Molecular Society (WMS).
2. American Society for Biochemistry and Molecular Biology (ASBMB). | ||
| Professional Experience: | ||
| --Graduate Research Assistant, The Graduate School and University Center 2011-2017
--Lecturer, Hunter College of CUNY 2013-2017 --Adjunct Assistant Professor, Borough of Manhattan Community College 2014-2020 --Postdoctoral Fellow, Memorial Sloan Kettering Cancer Center 2017-2020 --Research Associate, Memorial Sloan Kettering Cancer Center 2020-2022 --Assistant Professor, Cleveland State University. 2022-Present | ||
| Research Grants: | ||
| a. NIH-1R00GM 145587--(2023-2025)
Gonzales (PI). Validation of an Introperative Neuro-Monitoring Contrast Agent for Cranial Nerves. b. NIH-1K99GM 145587--(2021-2022) Gonzales (PI). Development of multi-modal agents from natural spider peptides for prostate cancer via sodium-channel NaV1.7. | ||