Publications:

Selected publications (in chronological order)  

1. Komarov P.G., Komarova E.A., Kondratov R.V., Christov-Tselkov K., Coon J.S., Chernov M.V., Gudkov A.V.(1999) A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy. Science, Sep 10, 285, 1733-37

2. Kondratov R.V., Komarov P.G., Becker Y., Ewenson A., Gudkov A.V. (2001) Proceedings of The National Academy of Sciences of U.S.A., 98(24), 14078-14083

3. Kondratov R.V., Chernov M.V., Kondratova A.A., Gorbacheva V., Gudkov A.V., and Antoch M.P. BMAL1-dependent circadian oscillation of nuclear CLOCK: posttranslational events induced by dimerization of transcriptional activators of the mammalian clock system. (2003) Genes and Development, August , 17(15), 1921-1932

4. Komarova, E.A., Kondratov R.V., Wang K., Christov K., Golovkina T.V., Goldblum J.R., and Gudkov A.V. Dual effect of p53 on radiation sensitivity in vivo: p53 promotes hematopoietic injury, but protects from gastrointestinal syndrome in mice  (2004) Oncogene, 23(19), 3265-71.

5. Singhi A., Kondratov R.V., Chernov M.V., and Gudkov A.V.  Selection-subtraction approach (SSA): universal genetic screening technique that enables negative selection. (2004) Proceedings of The National Academy of Sciences of U.S.A., 101(25), 9327-32

6. Gorbacheva V.Y., Kondratov R.V., Zhang R., Gudkov A.V., Takahashi J.S., and Antoch M.P. (2005) Circadian control of drug response: mouse sensitivity to chemotherapeutic drug cyclophosphamide is modulated by the functional status of CLOCK/BMAL1 transactivation complex.  Proceedings of The National Academy of Sciences of U.S.A., 102(9), 3407-3412

7. Kondratov R.V*., Kondratova A.A., Lee C., Gorbacheva V.Y., Chernov M.V., and Antoch M.P. Posttranslational regulation of circadian CLOCK(NPAS2)/BMAL1 complex by CRYPTOCHROMES. (2006), Cell Cycle, 5(8), 890-895

8. Kondratov R.V*., Kanagal R., Kondratova A.A., Gorbacheva V. Y., and Antoch M. P. Dual role of CLOCK/BMAL1 circadian complex in the transcription control. (2006) FASEB J.,  20(3), 530-532

9. Kondratov R.V*., Kondratova A.A., Gorbacheva V.Y., Vykhovanets O.V. and Antoch M.P.  Early aging and age-related pathologies in mice deficient in BMAL1, the core component of the circadian clock. (2006) Genes and Development, 20(14), 1868-1873

10. Kondratov R.V. A role of the circadian system and circadian proteins in aging. (2007) Ageing Research Review, 6(1), 12-27

11. Kondratov R.V. and Antoch M.P. Circadian proteins in the regulation of cell cycle and genotoxic stress responses. (2007), Trends in Cell Biology, 17(7), 311-317

12. Kondratov R.V,* Vykhovanets O, Kondratova AA, Antoch MP. (2009)  Antioxidant N-acetyl-L-cysteine ameliorates symptoms of premature aging associated with the deficiency of the circadian protein BMAL1. Aging (Albany NY). 1(12):979-87.

13. Antoch MP and Kondratov R.V. (2010)  Circadian proteins and genotoxic stress response. Circ Res. 106(1):68-78. Review.

14. Kondratova A.A.,Dubrovsky Yu., Antoch M.P. & Kondratov R.V. (2010) Circadian clock controls adaptation to novel environment and memory formation. Aging (Albany NY).  2(5), 285-297

15. Khapre R., Samsa W., & Kondratov R.V. (2010) Circadian regulation of cell cycle: molecular connection between circadian clock and aging. Annals of Medicine. 42(6), 404-415
35. Dubrovsky Yu. Samsa W., & Kondratov R.V. (2010) Deficiency of circadian protein CLOCK reduces lifespan and increases age-related cataract development in mice. Aging (Albany NY).  2(12), 936-944

16. Khapre R.V., Kondratova A.A., Susova O.S., & Kondratov R.V. (2011) Circadian clock protein BMAL1 regulates cellular senescence in vivo. Cell Cycle 10(23), 4162-4169

17. Jeyaraj D., Haldar S.M., Wan X., McCauley M.D, Ripperger J.A., Hu K., Lu Y., Eapen B.L., Sharma N., Ficker E., Cutler M.J., Gulick J., Sanbe A., Robbins J., Demolombe S., Kondratov R.V., Shea S.A., Albrecht U., Wehrens X.H.T., Rosenbaum D.S. and Jain M.K. (2012) Circadian rhythms govern cardiac repolarization and arrhythmogenesis. Nature, 483, 96-99

18. Kondratova A.A. & Kondratov R.V. (2012) Circadian clock and pathologies of ageing brain. Nature Reviews Neuroscience 13, 325-335

19. Kondratov R.V. (2012) Cell-autonomous circadian DNA damage response: is the case closed? Cell cycle, 11(20)

* - co-correspondence author.