Jingqi Yan (Jingqi Yan), Ph. D.
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 Title: Assistant Professor
 Dept: Biological, Geological and Environmental Sciences
 Office: SR 284
 Phone: 216-687-2411
 Email: j.yan37@csuohio.edu
 Address: 2121 Euclid Ave. SR 284, Cleveland, OH 44115

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Education:
Ph.D., Neuroscience and Biophysics, The Biophysics Institute, Chinese Academy of Science
 
Brief Bio:
Jingqi Yan received his Ph.D. from the Brain & Cognition Research Center of the Biophysics Institute, Chinese Academy of Science. From 2013 to 2021, he was a post-doctoral fellow and promoted to Instructor at Albert Einstein College of Medicine with Prof. Dongsheng Cai and Prof. R. Suzanne Zukin. In 2020, Dr. Yan joined Cleveland State University as an Assistant Professor in the Department of Biology, Geology, and Environmental Science (BGES) and a member of the Center for Gene Regulation in Health and Disease (GRHD).
 
Research Interests:
My research interest is to understand the cellular and molecular mechanisms underlying cell-cell communications (secreting factors, synapses┬┐) in the brain, and the roles of these communications in brain function and pathophysiology of autism and metabolic disorders.

Autism spectrum disorders (ASDs) are a group of developmental disorders. In 2020, approximately 1 in 54 children in the U.S. is diagnosed with autism, according to the Centers for Disease Control and Prevention (CDC). Fragile X syndrome (FXS) is the leading genetic cause of autism and the most common form of heritable intellectual disabilities.  The prevalence of Fragile X syndrome is estimated as 1 in 3,000 in males and as 1 in 6,000 in females. Patients with autism exhibit complex and debilitating neurological phenotypes, including impaired cognition, hyperactivity to sensory stimuli, and social deficits. Effective treatment for ASDs and Fragile X syndrome is still lacking.

Currently, our research is focused on investigating how autophagy and exosomes regulate brain synaptic transmission and neural circuits controlling sensory, cognition, and behaviors. Findings from our research are expected to develop novel therapeutic strategies for cognitive and social deficits associated with autism spectrum disorders.