Publications:

Selected peer-reviewed publications (in chronological order):

1. Maher, S.; Kalil, H.; Liu, G.; Sossey-Alaoui, K.; Bayachou, M. ¿Alginate-Based Hydrogel Platform Embedding Silver Nanoparticles and Cisplatin: Characterization of the Synergistic Effect on a Breast Cancer Cell Line¿ Front. Mol. Biosciences  (Nanobiotechnology, 2023, Vol. 10, DOI: 10.3389/fmolb.2023.1242838.
2. Maher, S.; Smith, L.A.; El-Khoury, C.A.; Kalil, H.; Sossey-Alaoui, K.; Bayachou, M. ¿Inducible Nitric Oxide Synthase Embedded in Alginate/Polyethyleneimine Hydrogel as a New Platform to Explore NO-Driven Modulation of Biological Function.¿ Molecules 2023, 28, 1612. https://doi.org/10.3390/molecules28041612
3. Gomaa I, Emam MH, Wassel AR, Ashraf K, Hussan S, Kalil H, Bayachou M, Ibrahim MA. ¿Microspheres with 2D rGO/Alginate Matrix for Unusual Prolonged Release of Cefotaxime.¿ Nanomaterials 2023 May 1;13(9):1527. doi: 10.3390/nano13091527.
4. Kalil, H.; Fouad, F.; Azeroual, S.; Bose,T; and Bayachou, M. ¿Bottom-up Design of a Grafted Organic Selenide Interface for Sensitive Electrocatalytic Detection of Peroxynitrite¿ ChemElectroChem, 2021; doi.org/10.1002/celc.202100375.
5. Cover Feature: Bottom-up Design of a Grafted Organic Selenide Interface for Sensitive Electrocatalytic Detection of Peroxynitrite; ChemElectroChem 17/2021.
6. Darwish ER, Kalil H, Alqahtani W, Moalla SMN, Hosny NM, Amin AS, Martin HB, Bayachou, M. ¿Fast and Reliable Synthesis of Melanin Nanoparticles with Fine-Tuned Metal Adsorption Capacities for Studying Heavy Metal Ions Uptake¿. Nanotechnol Sci Appl. 2021; 14:101-111 doi.org/10.2147/NSA.S296722
7. Balaraman, L.; Emhoff, K.; Salem,A.; Hanna, J.; Alsabony, M.; Bayachou, M.; Mundell, J.; Boyd, W. ¿Electrochemical studies of cobalt(II) diphenylazodioxide complexes¿ Inorganica Chimica Acta, doi.org/10.1016/j.ica.2019.119277
8. Kalil, H.; Maher, S.; Bose, T.; and Bayachou, M. ¿Manganese Oxide/Hemin-Functionalized Graphene as a Platform for Peroxynitrite Sensing¿ Journal of the Electrochemical Society, 165: G3133-G3140, 2018 DOI: 10.1149/2.0221812jes
9. Janine Mauzeroll, Lili Deligianni, and Mekki Bayachou, Editors, Focus Issue ¿Brain and Electrochemistry¿ Summer 2018 (Electrochemical Society) JES, Vol 165, issue 12, 2018
10. Gunasekera, B.; AbouDiwan, C.; Altawallbeh, G.; Kalil, H.; Maher, S.; Xu, S.; Bayachou, M. ¿Functional Layer-by-Layer Thin Films of Inducible Nitric Oxide (NO) Synthase Oxygenase and Polyethylenimine: Modulation of Enzyme Loading and NO- Release Activity¿ ACS Applied Materials & Interfaces, 2018 DOI 10.1021/acsami.7b17575
11. Haque, M.M; Tejero, J.; Bayachou, M.; Kenney, C.T.; Stuehr, D.J. ¿A cross-domain charge interaction governs the activity of NO synthase¿ J. Biol. Chem. 293:4545-4554, 2018.
12. AlTawallbeh,G; Haque, M.M; Streletzky, K.A.; Stuehr, D.; Bayachou, M. ¿Endothelial nitric oxide synthase oxygenase on lipid nanodiscs: A nano-assembly reflecting native-like function of eNOS¿ Biochem. and Biophys. Res. Comm. 493, 1438-42, 2017.
13. Bayachou M, Burgess J. Electrons as "Agents" and "Signals" of Change in Organic Chemistry, Biology, and Beyond. The Electrochemical Society interface. 2016 August; 25(2):35.
14. Bayachou, M. Editor (with Szunerits and Peteu) Book ¿Peroxynitrite Detection in Biological Media: Challenges and Advances¿ Royal Society of Chemistry Publishing, Cambridge, (ISBN 1782620850) 2015.
15. Bayachou, M, Altawallbeh, G.; Kalil, H.; Wojciechowski, S.; Bose, T. ¿Methods of Peroxynitrite Synthesis in the Context of the Development and Validation Peroxynitrite Sensors¿ in ¿Peroxynitrite Detection in Biological Media: Challenges and Advances¿ Royal Society of Chemistry Publishing, Cambridge, CB4 0WF, UK, 2015
16. Banihani SA, Bayachou M, Alzoubi K. J ¿L-carnitine is a calcium chelator: a reason for its useful and toxic effects in biological systems.¿ Basic Clin. Physiol. Pharmacol., 26(2), 141-5, 2015.
17. Haque, M.M; Bayachou, M.; Tejero, J.; Kenney, C.T.; Waskell, L., Stuehr, D.J. ¿Distinct conformational behaviors of four mammalian dual-flavin reductases (cytochrome P450 reductase, methionine synthase reductase, neuronal nitric oxide synthase, endothelial nitric oxide synthase) determine their unique catalytic profiles¿ FEBS J. 281(23), 5325-5340, 2014
18. Banihani S.; Bayachou, M. ¿Salvia fruticosa reduces intrinsic cellular and H2O2-induced DNA oxidation in HEK 293 cells; assessment using flow cytometry.¿ Asian Pac J Trop Biomed. 4(5), 399-403, 2014
19. Banihani, S.; Agarwal, A.; Sharma, R.; Bayachou, M. ¿Cryoprotective effect of l-carnitine on motility, vitality and DNA oxidation of human spermatozoa.¿ Andrologia 46(6), 637-641, 2014
20. Haque, M. M.; Tejero, J.; Bayachou, M.; Wang, Z. Q.; Fadlalla, M.; Stuehr, D. J., ¿Thermodynamic characterization of five key kinetic parameters that define neuronal nitric oxide synthase catalysis.¿ FEBS J. 280, 4439-53, 2013
21. Oprea, R.; Peteu, S. F.; Subramanian, P.; Qi, W.; Pichonat, E.; Happy, H.; Bayachou, M.; Boukherroub, R.; Szunerits, S., ¿Peroxynitrite activity of hemin-functionalized reduced graphene oxide.¿ Analyst 138, 4345-52, 2013
22. Peteu, S.; Bose, T.; Bayachou, M. ¿Polymerized Hemin as an Electrocatalytic Platform for Peroxynitrite's Oxidation and Detection¿ Anal. Chim. Acta 780, 81-88, 2013
23. Haque, M.M.; Bayachou, M.; Fadlalla, M.A. Durra, D.; Stuehr, D.J. ¿Charge Pairing interactions control the conformational setpoint and motions of the FMN domain in neuronal nitric oxide synthase¿ Biochem J. 450, 607-17, 2013.
24. Saleh, S., Moreno-Molek, S. Perera, I., Riga, A., Sam-Yellowe, T., and Bayachou, M. ¿Probe functionalization with Rhop-3 antibody: toward a Rhop-3 antigen immunosensor for the detection of malaria¿ Anal. & Bional. Chem. 402, 2379-2384, 2012 (*Saleh: Undergrad Student)
25. Perera, Reshani H.; Peiris, Pubudu M.; Peteu, Serban F.; Bayachou, Mekki ¿Nitric Oxide Synthase Encapsulation in Liposomes: a Potential Delivery Platform to (Nitric Oxide)-Deficient Targets¿ Electroanalysis 24, 37-41, 2012.
26. Invited Book Chapter: Peteu, S.F.; Banihani, S.; Gunesekera, M.M., Peiris, P., Sicuia, O.A.; Bayachou, M. ¿Peroxynitrite and Nitroxidative Stress: Detection Probes and Micro-Sensors. A Case of a Nanostructured Catalytic Film¿ In ¿Oxidative Stress: Diagnostics, Prevention, and Therapy. January 1, 2012, 311-339.
27. Bani Hani, S., Agarwal, A., Sharma, R., Bayachou, M. ¿Human sperm DNA oxidation, motility and viability in the presence of L-carnitine during in vitro incubation and centrifugation¿ Andrologia, 26 SEP 2011, DOI: 10.1111/j.1439-0272.2011.01216.x, 2011
28. Peteu, S.; Peiris, P.; Gebremichael, E.; Bayachou, M., Nanostructured poly(3,4-ethylenedioxythiophene)-metalloporphyrin films: Improved catalytic detection of peroxynitrite. Biosensors and Bioelectronics 25, 1914-1921, 2010. (* Gebremichael Ermias: Undergrad Student)
29. Zanati, N.; Mathews, M.E.; Perera, I.N.; Moran, J.J.; Boutros, J.A.; Riga, A.T.; Bayachou, M. ¿Cholesterol levels and activity of membrane bound proteins: characterization by thermal and electrochemical methods¿ J. Therm. Anal. Cal. 96, 669-672, 2009. (* Noufissa Zanati and Ellen Mathews are both Undergrad Students)
30. Perera, N.I.; Sabbagh, T.; Boutros, J. A.; Bayachou, M. ¿Reductive Decomposition of a Diazonium Intermediate by Dithiothreitol Affects the Determination of NOS Turnover Rates¿ Talanta 78, 910-915, 2009.
31. He, P.; Bayachou, M. ¿Layer-by-layer fabrication and characterization of DNA-wrapped single-walled carbon nanotubes¿Langmuir, 2005, 21, 6086-6092
32. Bayachou, M.; Boutros, J. ¿Direct electron transfer to the oxygenase domain of neuronal nitric oxide synthase (NOS): Exploring unique redox properties of NOS enzymes¿, J. Am. Chem. Soc., 2004, 126, 12722
33. Boutros, J.; Bayachou, M. ¿Myoglobin as an efficient electrocatalyst for nitromethane reduction¿ Inorg. Chem., 2004, 43, 3847
34. Perera, I.; Bayachou, M. ¿Eliminating absorbing interference using the H-point standard addition method: case of Griess assay in the presence of interferent heme enzymes such as NOS¿ Anal. Bioanal. Chem., 2004, 379, 1055
35. Imoos, C.E.; Chou, J.; Bayachou, M.; Farmer, P.J. ¿Electrocatalytic reductions of nitrite, nitric oxide, and nitrous oxide by thermophilic cytochrome P450CYP119 in film-modified electrodes and an analytical comparison of its catalytic activities with myoglobin¿ J. Am. Chem. Soc., 2004, 126, 4934
36. Bayachou, M.; Lhadi, E.L.K.; Farmer P.J."Catalytic two-electron reductions of Nitrous oxide and azide by myoglobin in surfactant films" Inorg. Chem. 2000, 39, 289
37. Farmer, P.J.; Lin, R.; Bayachou, M. "Electrochemistry and Catalysis by Myoglobin in Surfactant Films" Comments Inorg. Chem. 1998, 20, 101.
38. Bayachou, M. Verpeaux, J.N., Buriez, O. Amatore, C. "Electron transfer catalysis of the hydrogenolysis of Cyclopentadienyl dicarbonyl acyl iron complexes by tributyltin hydride" J. Organomet. Chem. 1998, 567, 25.
39. Bayachou, M.; Lin, R.; Cho, W.; Farmer, P.J. "Electrochemical Reduction of NO by Myoglobin in Surfactant Film: Characterization and Reactivity of the Nitroxyl (NO-) Adduct" J. Amer. Chem. Soc. 1998, 120, 9888.
40. Lin, R.; Bayachou, M.; Greaves, J.; Farmer, P.J. "Nitrite Reduction by Myoglobin in Surfactant Films" J. Amer. Chem. Soc. 1997, 119, 12689.
41. Bayachou, M., Amatore, C., Fiedler, J.; Pospisil, L.; Verpeaux, J.N. "Electrochemical Carbonylation of Organoiron Methyl Complex: A Study of Reaction Intermediates" J. Electroanal. Chem., 1995, 387, 101.

Patents:
1. Bayachou, M. Peiris, P. ¿Immobilized nanostructured catalyst for ultra-sensitive nitric oxide detection¿ 2007, International patent application # PCT/US07/82251, US application # 11877454; Awarded, March, 23rd, 2011
2. Bayachou, M. Abou Diwan, C. "Nitric Oxide Release from Coatings Incorporating Nitric Oxide Synthase Enzyme ". 2008, Full patent, #WO/2009/073643; PCT/US2008/085224