Publications:

Opoku E, Traughber CA, Zhang D, Iacano AJ, Khan M, Han J, Smith JD, Gulshan K*. Gasdermin D Mediates Inflammation-Induced Defects in Reverse Cholesterol Transport and Promotes Atherosclerosis. Front Cell Dev Biol. 2021;9:715211. doi: 10.3389/fcell.2021.715211. eCollection 2021. PubMed PMID: 34395445; PubMed Central PMCID: PMC8355565.(*Corresponding author).

Traughber CA, Opoku E, Brubaker G, Major J, Lu H, Lorkowski SW, Neumann C, Hardaway A, Chung YM, Gulshan K, Sharifi N, Brown JM, Smith JD. Uptake of high-density lipoprotein by scavenger receptor class B type 1 is associated with prostate cancer proliferation and tumor progression in mice. J Biol Chem. 2020 Jun 12;295(24):8252-8261. doi: 10.1074/jbc.RA120.013694. Epub 2020 May 1. PubMed PMID: 32358065; PubMed Central PMCID: PMC7294086.

Brubaker G, Lorkowski SW, Gulshan K, Hazen SL, Gogonea V, Smith JD. First eight residues of apolipoprotein A-I mediate the C-terminus control of helical bundle unfolding and its lipidation. PLoS One. 2020;15(1):e0221915. doi: 10.1371/journal.pone.0221915. eCollection 2020. PubMed PMID: 31945064; PubMed Central PMCID: PMC6964839.

Iacano AJ, Lewis H, Hazen JE, Andro H, Smith JD, Gulshan K*. Miltefosine increases macrophage cholesterol release and inhibits NLRP3-inflammasome assembly and IL-1ß release. Sci Rep. 2019 Jul 31;9(1):11128. doi: 10.1038/s41598-019-47610-w. PubMed PMID: 31366948; PubMed Central PMCID: PMC6668382.(*Corresponding author).

Lorkowski SW, Brubaker G, Gulshan K, Smith JD. V-ATPase (Vacuolar ATPase) Activity Required for ABCA1 (ATP-Binding Cassette Protein A1)-Mediated Cholesterol Efflux. Arterioscler Thromb Vasc Biol. 2018 Nov;38(11):2615-2625. doi: 10.1161/ATVBAHA.118.311814. PubMed PMID: 30354238; PubMed Central PMCID: PMC6209108.

Huang Y, Gulshan K, Nguyen T, Wu Y. Biomarkers of Cardiovascular Disease. Dis Markers. 2017;2017:8208609. doi: 10.1155/2017/8208609. Epub 2017 Nov 7. PubMed PMID: 29238120; PubMed Central PMCID: PMC5697130.

Kasumov T, Li L, Li M, Gulshan K, Kirwan JP, Liu X, Previs S, Willard B, Smith JD, McCullough A. Ceramide as a mediator of non-alcoholic Fatty liver disease and associated atherosclerosis. PLoS One. 2015;10(5):e0126910. doi: 10.1371/journal.pone.0126910. eCollection 2015. PubMed PMID: 25993337; PubMed Central PMCID: PMC4439060.

-Gulshan K*, Brubaker G, Conger H, Wang S, Zhang R, Hazen SL, Smith JD*.PI(4,5)P2 Is Translocated by ABCA1 to the Cell Surface Where It Mediates Apolipoprotein A1 Binding and Nascent HDL Assembly.  Circulation Research. 2016 Sep 16;119(7):827-38. (*Corresponding author).

-Wang S, Robinet P, Smith JD, Gulshan K *. Free-cholesterol-mediated autophagy of ORMDL1 stimulates sphingomyelin biosynthesis.
. Autophagy. 2015 Jun 4:0.(*Corresponding author).

-Wang S, Robinet P, Smith JD*, Gulshan K *.. ORMDL orosomucoid-like proteins are degraded by free-cholesterol-loading-induced autophagy.  PNAS. 2015 Mar 24;112(12):3728-33.(*Corresponding author).

-Gulshan K, Brubaker G, Wang S, Hazen SL, Smith JD. Sphingomyelin depletion impairs anionic phospholipid inward translocation and induces cholesterol efflux.  J Biol Chem. 2013 Dec
27;288(52):37166-79.

-Thakur JK, Arthanari H, YangF, Pan S, Fan X, Breger J, Frueh D, Gulshan K, Li DK, Mylonakis E, Struhl K, Moye-Rowley WS,Cormack BP, Wagner G, Näär AM. A nuclear receptor-like pathway regulating multidrug resistance in fungi.  Nature. 2008 Apr 3;452(7187):604-9.

-Gulshan K, Moye-Rowley WS. Multidrug resistance in fungi. (Review, one of 20 most read articles in Eukaryotic Cell, Nov. 2007) Eukar Cell. 2007 Nov;6(11):1933-42.

-Kailash Gulshan Sharma, Mason DL, Liu G, Rea PA, Bachhawat AK, Michaelis S. Localization, regulation, and substrate transport properties of Bpt1p, a Saccharomyces cerevisiae MRP-type ABC transporter.  Eukar Cell. 2002 Jun;1(3):391-400.

https://pubmed.ncbi.nlm.nih.gov/?term=Kailash+Gulshan&sort=date&size=50