Co-Investigator of Clinical Trials at Case Comprehensive Cancer Center

  • Yan Xu (Participant)

Activity: OtherProfessional Service

Description

Co-Investigator for the following clinical trials 1. Case 1Y05: Methoxyamine and Temozolomide in Treating Patients With Advanced Solid Tumors (PI, Jennifer Eads) 2. Case 2Y10: Methoxyamine and Fludarabine Phosphate in Treating Patients With Relapsed or Refractory Hematologic Malignancies (PI, Paolo Caimi) 3. Case 2411: Silicon Phthalocyanine 4 and Photodynamic Therapy in Stage IA-IIA Cutaneous T-Cell Non-Hodgkin Lymphoma (PI, Elma Baron) 4. Case 5913: Curcumin and Cholecalciferol in Treating Patients With Previously Untreated Stage 0-II Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma (PI, Basem William) Development and validation of LC-MS/MS methods in collaborations with investigators at CWRU and CCF 1. Simultaneous determination of trimethylamine N-oxide (TMAO), L-carnitine and choline in human plasma (Li Li, CWRU) 2. Simultaneous Determination of dihydrotestosterone and its metabolites in mouse tissue and serum (Monica Montano, CWRU) 3. ATP/ADP, NAD/NADH, NADP/NADPH, ATP/dATP (John Wang, CWRU; Junran Zhang, CWRU) 4. Simultaneous determination of 25-hydroxyvitamin D3, curcumin and its metabolites in human plasma (Basem William, CWRU) 5. Simultaneous determination of decitabine, 5mdC and dNs from human DNA after administration of decitabine (Yogen Saunthararajah, CCF)
Period20132014
Held atCase Comprehensive Cancer Center, CWRU