Absolute Structure of 2’-Desacetoxyaustrospicatine Established by X-Ray Analysis and Circular Dichroism Spectroscopy

Yaeko Konda; Tomomitsu Sasaki; Hiroaki Takayanagi; Yoshihiro Harigaya; Xue Long Sun; Xian Li; Masayuki Onda

doi:10.1248/cpb.42.2621

Absolute Structure of 2’-Desacetoxyaustrospicatine Established by X-Ray Analysis and Circular Dichroism Spectroscopy

Yaeko Konda
, Tomomitsu Sasaki
, Hiroaki Takayanagi
, Yoshihiro Harigaya
, Xue Long Sun
, Xian Li
, Masayuki Onda

Chemistry

Research output: Contribution to journal › Article

Abstract

Three taxane diterpenes, taxinine (1), taxinine B (2), and 2’-desacetoxyaustrospicatin (3), have been isolated from Taxus cuspidata Siebet Zucc. The absolute stereostructure of 3 has been determined by a combination of X-ray analysis and circular dichroism (CD) spectroscopy. Complete assignments of 1H- and 13C-nuclear magnetic resonance (NMR) signals for 1 and 2 have been made on the basis of two-dimensional (2D) NMR techniques. © 1994, The Pharmaceutical Society of Japan. All rights reserved.

Original language	English
Journal	Chemical and Pharmaceutical Bulletin
Volume	42
Issue number	Issue 12
DOIs	https://doi.org/10.1248/cpb.42.2621
State	Published - 1994

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10.1248/cpb.42.2621

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title = "Absolute Structure of 2{\textquoteright}-Desacetoxyaustrospicatine Established by X-Ray Analysis and Circular Dichroism Spectroscopy",

abstract = "Three taxane diterpenes, taxinine (1), taxinine B (2), and 2{\textquoteright}-desacetoxyaustrospicatin (3), have been isolated from Taxus cuspidata Siebet Zucc. The absolute stereostructure of 3 has been determined by a combination of X-ray analysis and circular dichroism (CD) spectroscopy. Complete assignments of 1H- and 13C-nuclear magnetic resonance (NMR) signals for 1 and 2 have been made on the basis of two-dimensional (2D) NMR techniques. {\textcopyright} 1994, The Pharmaceutical Society of Japan. All rights reserved.",

author = "Yaeko Konda and Tomomitsu Sasaki and Hiroaki Takayanagi and Yoshihiro Harigaya and Sun, \{Xue Long\} and Xian Li and Masayuki Onda",

year = "1994",

doi = "10.1248/cpb.42.2621",

language = "English",

volume = "42",

journal = "Chemical and Pharmaceutical Bulletin",

number = "Issue 12",

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TY - JOUR

T1 - Absolute Structure of 2’-Desacetoxyaustrospicatine Established by X-Ray Analysis and Circular Dichroism Spectroscopy

AU - Konda, Yaeko

AU - Sasaki, Tomomitsu

AU - Takayanagi, Hiroaki

AU - Harigaya, Yoshihiro

AU - Sun, Xue Long

AU - Li, Xian

AU - Onda, Masayuki

PY - 1994

Y1 - 1994

N2 - Three taxane diterpenes, taxinine (1), taxinine B (2), and 2’-desacetoxyaustrospicatin (3), have been isolated from Taxus cuspidata Siebet Zucc. The absolute stereostructure of 3 has been determined by a combination of X-ray analysis and circular dichroism (CD) spectroscopy. Complete assignments of 1H- and 13C-nuclear magnetic resonance (NMR) signals for 1 and 2 have been made on the basis of two-dimensional (2D) NMR techniques. © 1994, The Pharmaceutical Society of Japan. All rights reserved.

AB - Three taxane diterpenes, taxinine (1), taxinine B (2), and 2’-desacetoxyaustrospicatin (3), have been isolated from Taxus cuspidata Siebet Zucc. The absolute stereostructure of 3 has been determined by a combination of X-ray analysis and circular dichroism (CD) spectroscopy. Complete assignments of 1H- and 13C-nuclear magnetic resonance (NMR) signals for 1 and 2 have been made on the basis of two-dimensional (2D) NMR techniques. © 1994, The Pharmaceutical Society of Japan. All rights reserved.

UR - https://dx.doi.org/10.1248/cpb.42.2621

U2 - 10.1248/cpb.42.2621

DO - 10.1248/cpb.42.2621

M3 - Article

VL - 42

JO - Chemical and Pharmaceutical Bulletin

JF - Chemical and Pharmaceutical Bulletin

IS - Issue 12

ER -

Absolute Structure of 2’-Desacetoxyaustrospicatine Established by X-Ray Analysis and Circular Dichroism Spectroscopy

Abstract

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