TY - JOUR
T1 - Biomimetic coating technology for orthopedic implants
AU - Koju, Naresh
AU - Sikder, Prabaha
AU - Ren, Yufu
AU - Zhou, Huan
AU - Bhaduri, Sarit B
PY - 2017/1/1
Y1 - 2017/1/1
N2 - Biomimetic coating process is one of the most versatile techniques developed for coating various orthopedic implant surfaces. The surface of an orthopedic implant, whether it is biodegradable or non-biodegradable, needs to be bioactive for osseointegration (direct bonding with bone). The above mentioned coating technique is employed to deposit a bone-like apatite (calcium phosphate) on the implant surfaces, so that the implants become more bioactive, resulting in osseointegration. Simulated body fluids (SBFs) play a critical role in this method. This short review describes and critiques the progresses made in this field by focusing on: Firstly, the compositional aspects of various SBFs; secondly, the strategies to enhance the coating kinetics; and finally, examples of coating various types of surfaces of implants fabricated from polymers and metals, both biodegradable and non-biodegradable in nature.
AB - Biomimetic coating process is one of the most versatile techniques developed for coating various orthopedic implant surfaces. The surface of an orthopedic implant, whether it is biodegradable or non-biodegradable, needs to be bioactive for osseointegration (direct bonding with bone). The above mentioned coating technique is employed to deposit a bone-like apatite (calcium phosphate) on the implant surfaces, so that the implants become more bioactive, resulting in osseointegration. Simulated body fluids (SBFs) play a critical role in this method. This short review describes and critiques the progresses made in this field by focusing on: Firstly, the compositional aspects of various SBFs; secondly, the strategies to enhance the coating kinetics; and finally, examples of coating various types of surfaces of implants fabricated from polymers and metals, both biodegradable and non-biodegradable in nature.
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U2 - 10.1016/j.coche.2016.11.005
DO - 10.1016/j.coche.2016.11.005
M3 - Review article
SN - 2211-3398
VL - 15
SP - 49
EP - 55
JO - Current Opinion in Chemical Engineering
JF - Current Opinion in Chemical Engineering
ER -