Design and synthesis of biotin chain-terminated glycopolymers for surface glycoengineering

Xue Sun; Keith M. Faucher; Michelle Houston; Daniel Grande; Elliot L. Chaikof

doi:10.1021/ja025788v

Design and synthesis of biotin chain-terminated glycopolymers for surface glycoengineering

Xue Sun
, Keith M. Faucher
, Michelle Houston
, Daniel Grande
, Elliot L. Chaikof

Chemistry

Emory University School of Medicine
Georgia Institute of Technology

Research output: Contribution to journal › Article › peer-review

105 Scopus citations

Abstract

Biotin chain-terminated glycopolymers were generated by cyanoxyl-mediated free-radical polymerization using a biotin-derivatized arylamine initiator with high conversion (75%) and low polydispersity (1.30). Streptavidin-biotinylated glycopolymer binding was verified by SDS-PAGE gel shift assay and patterned glycocalyx-mimetic surfaces successfully fabricated. Copyright © 2002 American Chemical Society.

Original language	English
Pages (from-to)	7258-7259
Number of pages	2
Journal	Journal of the American Chemical Society
Volume	124
Issue number	25
DOIs	https://doi.org/10.1021/ja025788v
State	Published - Jun 26 2002

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title = "Design and synthesis of biotin chain-terminated glycopolymers for surface glycoengineering",

abstract = "Biotin chain-terminated glycopolymers were generated by cyanoxyl-mediated free-radical polymerization using a biotin-derivatized arylamine initiator with high conversion (75\%) and low polydispersity (1.30). Streptavidin-biotinylated glycopolymer binding was verified by SDS-PAGE gel shift assay and patterned glycocalyx-mimetic surfaces successfully fabricated. Copyright {\textcopyright} 2002 American Chemical Society.",

author = "Xue Sun and Faucher, \{Keith M.\} and Michelle Houston and Daniel Grande and Chaikof, \{Elliot L.\}",

year = "2002",

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AU - Faucher, Keith M.

AU - Houston, Michelle

AU - Grande, Daniel

AU - Chaikof, Elliot L.

PY - 2002/6/26

Y1 - 2002/6/26

N2 - Biotin chain-terminated glycopolymers were generated by cyanoxyl-mediated free-radical polymerization using a biotin-derivatized arylamine initiator with high conversion (75%) and low polydispersity (1.30). Streptavidin-biotinylated glycopolymer binding was verified by SDS-PAGE gel shift assay and patterned glycocalyx-mimetic surfaces successfully fabricated. Copyright © 2002 American Chemical Society.

AB - Biotin chain-terminated glycopolymers were generated by cyanoxyl-mediated free-radical polymerization using a biotin-derivatized arylamine initiator with high conversion (75%) and low polydispersity (1.30). Streptavidin-biotinylated glycopolymer binding was verified by SDS-PAGE gel shift assay and patterned glycocalyx-mimetic surfaces successfully fabricated. Copyright © 2002 American Chemical Society.

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JF - Journal of the American Chemical Society

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Design and synthesis of biotin chain-terminated glycopolymers for surface glycoengineering

Abstract

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