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Novel practical synthesis of Kdn2en and its C-4 nitrogen-modified derivatives

  • Xue Sun
  • , Noriko Sato
  • , Toshitsugu Kai
  • , Kimio Furuhata
  • Kitasato University

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

A practical synthesis of Kdn2en and 4-amino-4-deoxy-Kdn2en has been achieved via a key intermediate, methyl 4,5,7,8,9-penta-O-acetyl-2,6-anhydro- 3-deoxy-D-glycero-D-galacto-non-2-enonate, which has been prepared from Kdn in three steps in 91% overall yield. (C) 2000 Elsevier Science Ltd.
Original languageEnglish
Pages (from-to)1-6
Number of pages6
JournalCarbohydrate Research
Volume323
Issue number1-4
DOIs
StatePublished - Jan 12 1999

Keywords

  • 4-Acylamino-4-deoxy-
  • Kdn2en
  • Sialyl glycals
  • iso-Sialyl glycals

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