Site-specific multivalent carbohydrate labeling of quantum dots and magnetic beads

Xue Sun; Wanxing Cui; Carolyn Haller; Elliot L. Chaikof

doi:10.1002/cbic.200400137

Site-specific multivalent carbohydrate labeling of quantum dots and magnetic beads

Xue Sun
, Wanxing Cui
, Carolyn Haller
, Elliot L. Chaikof

Chemistry

Emory University School of Medicine

Research output: Contribution to journal › Article › peer-review

98 Scopus citations

Abstract

Glyco-imaging/biocapture. Glycopolymer-based multivalent carbohydrates facilitate high binding affinity and specificity of carbohydrate-protein interactions. Herein, we report site-specific multivalent carbohydrate labeling of quantum-dot and magnetic-bead surfaces using a biotin chain-end- functionalized glycopolymer and demonstrate the potential value of these multivalent carbohydrates in both imaging and biocapture applications.

Original language	English
Pages (from-to)	1593-1596
Number of pages	4
Journal	ChemBioChem
Volume	5
Issue number	11
DOIs	https://doi.org/10.1002/cbic.200400137
State	Published - Nov 5 2004

Keywords

Biocapture
Biopolymers
Lectin
Magnetic beads
Quantum dots

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10.1002/cbic.200400137

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keywords = "Biocapture, Biopolymers, Lectin, Magnetic beads, Quantum dots",

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AU - Cui, Wanxing

AU - Haller, Carolyn

AU - Chaikof, Elliot L.

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AB - Glyco-imaging/biocapture. Glycopolymer-based multivalent carbohydrates facilitate high binding affinity and specificity of carbohydrate-protein interactions. Herein, we report site-specific multivalent carbohydrate labeling of quantum-dot and magnetic-bead surfaces using a biotin chain-end- functionalized glycopolymer and demonstrate the potential value of these multivalent carbohydrates in both imaging and biocapture applications.

KW - Biocapture

KW - Biopolymers

KW - Lectin

KW - Magnetic beads

KW - Quantum dots

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Site-specific multivalent carbohydrate labeling of quantum dots and magnetic beads

Abstract

Keywords

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