TY - JOUR
T1 - Synthesis of 4-oxo and 4-hydroxyimino-4-deoxy-Kdn2en derivatives
AU - Sun, Xue
AU - Kai, Toshitsugu
AU - Sato, Noriko
AU - Takayanagi, Hiroaki
AU - Furuhata, Kimio
PY - 1999/1/1
Y1 - 1999/1/1
N2 - 2,6-Anhydro-3-deoxy-D-manno-non-2-en-4-ulosonic acid (4-oxo-Kdn2en, 2) was synthesized from methyl 2,6-anhydro-3-deoxy-D-glycero-D-galacto-non-2-enonate (Kdn-2en methyl ester, 7) by the oxidation with manganese dioxide in dry acetone in good yield. 4-Hydroxyimino-Kdn2en derivatives (3), and 4-carbethoxymethylene-Kdn2en derivatives (4) were synthesized from the peracetylated methyl ester of 4-oxo-Kdn2en by oximation and Wittig reaction in good yield, respectively.
AB - 2,6-Anhydro-3-deoxy-D-manno-non-2-en-4-ulosonic acid (4-oxo-Kdn2en, 2) was synthesized from methyl 2,6-anhydro-3-deoxy-D-glycero-D-galacto-non-2-enonate (Kdn-2en methyl ester, 7) by the oxidation with manganese dioxide in dry acetone in good yield. 4-Hydroxyimino-Kdn2en derivatives (3), and 4-carbethoxymethylene-Kdn2en derivatives (4) were synthesized from the peracetylated methyl ester of 4-oxo-Kdn2en by oximation and Wittig reaction in good yield, respectively.
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U2 - 10.1080/07328309908544060
DO - 10.1080/07328309908544060
M3 - Article
SN - 0732-8303
VL - 18
SP - 1131
EP - 1138
JO - Journal of Carbohydrate Chemistry
JF - Journal of Carbohydrate Chemistry
IS - 9
ER -