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Nolan Holland, Ph.D.
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| Research Keywords: |
| Biosynthesis of responsive polymers,
Elastin like polypeptides,
Atomic Force Microscopy AFM,
Circular dichroism spectroscopy,
Surface pressure isotherms,
Surface modification,
Antifreeze proteins,
Biomaterials,
Protein design & expression,
High performance liquid chromatography HPLC,
Ice crystal growth,
Biologically based materials,
Tissue Engineering Scaffolds,
Drug delivery hydrogel particles,
Protein Nuclear Magnetic Resonance (NMR) Spectroscopy,
Polymer micelles,
Theranostics |
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| Education: |
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Ph.D., Macromolecular Science, Case Western Reserve University, 1999
M.S., Macromolecular Science, Case Western Reserve University, 1996
B.S., Polymer Science & Engineering, Case Western Reserve University, 1994
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| Brief Bio: |
| Before joining the Chemical and Biomedical Engineering Department in 2004, Professor Holland performed postdoctoral research for five years in three different laboratories. In Biomedical Engineering at Case Western Reserve University, he investigated poly(ethylene oxide) materials as biomedical coatings and for drug delivery applications. As a Humboldt fellow at the Ludwig-Maximilians-University in Munich, Germany, he worked in the laboratory of Hermann Gaub investigating single molecules with atomic force microscopy. He returned to Case Western Reserve University, this time in the Physiology & Biophysics Department in the Medical School, to investigate the structure of antifreeze proteins using nuclear magnetic resonance (NMR) spectroscopy. Prof. Holland earned his B.S., M.S., and Ph.D. degrees in the Macromolecular Science Department at Case Western Reserve University. |
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| Honors and Awards: |
| Fenn College of Engineering Outstanding Research Faculty Award (2010)
Chemical & Biomedical Engineering Most Outstanding Faculty Member (2009)
NIH Postdoctoral Traineeship (2002-2004)
Alexander von Humboldt Postdoctoral Research Fellowship (2000-2001)
Graduate Student Symposium Oral Competition Finalist (1999)
Society for Biomaterials Whitaker Travel Award (1997, 1998, 2000)
American Society for Artificial Internal Organs Travel Fellowship (1995)
Graduate Traineeship (Whitaker Foundation)
NSF Graduate Fellowship Honorable Mention (1994)
Samuel Maron Memorial Award (1994; Outstanding Senior in Polymer Engineering)
Hal Loranger Award for Polymer Science (1994; Undergraduate Research)
Albert W. Smith Scholarship (1990-1994)
Caroline Knox Foundation Scholarship (1990-1994)
Elks National Scholarship (1990)
Stevenson Scholarship (1990) |
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| Research Interests: |
| Antifreeze protein for tissue/organ preservation
Responsive polymers
Biosynthesis of protein-based polymers
Mechanics of single biomolecules |
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| Teaching Areas: |
| Biomaterials
Polymers
Materials Science
Tissue Engineering
Interfacial Phenomena
Medical Device Design |
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| Professional Affiliations: |
| Society for Biomaterials
American Chemical Society
American Association for the Advancement of Science
Tau Beta Pi |
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| Professional Experience: |
| Department of Chemical & Biomedical Engineering
Cleveland State University, Cleveland, OH
Assistant Professor August 2004-August 2009
Associate Professor August 2009-present
Department of Physiology & Biophysics
Case Western Reserve University, Cleveland, OH
Research Associate November 2001-August 2004
Department of Physics
John Carroll University, University Heights, OH
Part-time Instructor August 2003-December 2003
Department of Physics, Chair of Applied Physics
Ludwig-Maximilians-University, Munich, Germany
Research Assistant January 2000-September 2001
Biomedical Engineering Department
Case Western Reserve University, Cleveland, OH
Research Assistant June 1999-December 1999 |
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| University Service: |
| College Faculty Secretary, 2004-2008
Applied Biomedical Engineering Steering Committee, 2004-present
Applied Biomedical Engineering Admissions Committee, 2006-present
Cellular and Molecular Medicine Coordinating Committee, 2005-present
Lubrizol Scholarship Selection Committee, 2005-2009
Chemical & Biomedical Engineering Department Chair Search Committee, 2005-2006
BGES Molecular Medicine Faculty Search Committee, 2005-2006
Graduate Admissions & Standards Committee, August 2007-August 2009
Industrial Research Advisory Group, August 2008-February 2009
Research Advisory Group (Convener), January-February 2009
Choose Ohio First Bioscience & Healthcare Coordinating Committee ¿ July 2008-present
Biomedical Engineering Masters Admissions Committee, August 2009-present
BME Faculty Search Committee, May 2010-March 2011
BME Faculty Search Committee, August 2012-present
Tau Beta Pi Faculty Advisor, October 2012-present |
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| Community Service: |
| Mentor for Gilmour Academy Catalyst Program
Mentor for Senior Project from Orange High School
Volunteer at Zelma George Family Shelter, Cleveland
Volunteer at Operation New Creation, New Orleans (flood recovery)
Volunteer at Greater Cleveland Habitat for Humanity |
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| Research Grants: |
| Stabilization of Plasma Membranes During Cold-Temperature Storage Using Antifreeze Proteins
American Heart Association, National Scientist Development Grant 7/2006-6/2010
Biosynthesis of Molecular Scale Responsive Materials
University Research Council, Faculty Research Development Program 7/2007-6/2008
Optimization of Biosynthesis and Purification of Proteins and Polypeptides
Cleveland State University Undergraduate Summer Research Program 5/2008-8/2008
Protecting Cell Membranes During Cold-Storage Using Antifreeze Proteins
Cleveland State University Undergraduate Summer Research Program 5/2009-8/2009
Synthesis and Characterization of Functional Molecular Building Blocks for Responsive Materials
NSF, Materials World Network 8/2009-7/2012
Design and Characterization of Thermally responsive Nanoparticles, CSU Undergraduate Summer Research (with K Streletzky, Physics Department), 5/2010-8/2010. |
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